Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take hydroxychloroquine with all of your drugs and health problems. What companies makes safest hydroxychloroquine What is plaquenil medicine What is hydroxychloroquin Trade Name Plaquenil. ® How is this drug used? Plaquenil is used to for the treatment of rheumatoid arthritis RA, some symptoms of lupus, childhood arthritis JIA, and other autoimmune is also used for the prevention or treatment of malaria caused by mosquito bites. What is the mechanism of action? This phase I trial studies the side effects and best dose of hydroxychloroquine in treating patients with solid tumors undergoing radiation therapy for bone metastases. Drugs, such as hydroxychloroquine, may make tumor cells more sensitive to radiation therapy Radiation Treatment for Cancer Lupus, as well as other systemic autoimmune illnesses such as rheumatoid arthritis or scleroderma, are chronic, lifelong diseases. Although not unusually susceptible to develop cancer, some patients with rheumatic diseases, in natural course of events, do develop other illnesses such as breast cancer. For all uses of hydroxychloroquine: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor. Plaquenil and radiation Chloroquine and hydroxychloroquine for cancer therapy, Hydroxychloroquine in Treating Patients With Solid Tumors. Chloroquin family Radiation therapy uses high-energy x-rays to kill tumor cells. Giving hydroxychloroquine together with temozolomide and radiation therapy may kill more tumor cells. PURPOSE This phase I/II trial is studying the side effects and best dose of hydroxychloroquine when given together with radiation therapy and temozolomide and to see how well they work in treating patients with newly diagnosed glioblastoma multiforme. Hydroxychloroquine, Radiation, and Temozolomide Treating.. What Should Lupus Patients Know About Radiation Treatment.. Protecting your eyesight when taking Plaquenil Lupus.. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Preclinical studies indicate autophagy inhibition with hydroxychloroquine HCQ can augment the efficacy of DNA-damaging therapy. The primary objective of this trial was to determine the maximum tolerated dose MTD and efficacy of HCQ in combination with radiation therapy RT and temozolomide TMZ for newly diagnosed glioblastoma GB. Most radiation doctors. Your skin will most likely feel softer and suppler with the use of creams and lotions. Using creams and lotions will not reduce how severe your skin reaction becomes. Creams and lotions may help your skin to feel more comfortable. You may use a skin cream or lotion up to 1-2 hours before your treatment.