In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Plaquenil and diabetic retinopathy P falciparum resistance to chloroquine What is the difference between hydroxychloroquine and chloroquine Sjogren's syndrome can be difficult to diagnose because the signs and symptoms vary from person to person and can be similar to those caused by other diseases. Side effects of a number of medications also mimic some signs and symptoms of Sjogren's syndrome. People with Sjogren’s syndrome can have more than dry eyes and mouth. The digestive system also may feel the effects of too little moisture. Fiber can help the intestines move. Flax seeds and quinoa pronounced keen-wah work wonders. 5. Liquids. Liquids are an all-important part of a Sjogren’s syndrome diet. Rheumatologists love to prescribe plaquenil for people who have either Sjogren's, or Lupus. It is apparently kind of a wonder-drug for Lupus, in that it actually prevents flares in the majority, or a large percentage, of people. It doesn't do that for Sjogren's, but they don't know what it does do, so they like to give it to you and see what. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Sjogren's i can't tolerate plaquenil The Risk of Retinal Toxicity with Plaquenil - Sjogren's, Things to Include in a Sjogren's Syndrome Diet Order plaquenil without rxQuinacrine with hydroxychloroquineAvoid sun with plaquenilChloroquine brand name indiaDoxycycline and plaquenil interactions Then it went away, and I haven't had any side effects since. Like Lynnwood said, if the GI distress keeps up for ten or more days, let your doctor know. I've also heard that some people who can't tolerate the generic of plaquenil hydroxychloroquine because of the GI upset do okay on the brand name Plaquenil. Plaquenil -. Hydroxychloroquine? - Symptoms and Medical Treatments.. Hydroxychloroquine User Reviews for Sjogren's. -. Plaquenil didn't help me at all and I barely tolerated it anyway. However, it seems like it might have been helping you. It might help to start tracking your pain and stiffness severity, what makes it better/worse, problems you are having lack of sleep, problems doing tasks. I took myself off of my plaquenil because I was feeling extra dizzy and I contributed it to the medication. Well, I was feeling SO bad with the Sjogrens and Lupus that I re-started it. SO far, SO good. Can I please ask, not so much with Lupus if you have that too, but what benefits they say the Plaquenil gives to Sjogrens? Thanks so much, as. I've done well with plaquinel, however my SLE and scleroderma symptoms are my main issues. With Sjogrens I've just got antibodies and dry eyes. I've also had next to nothing in terms of side effects that I've noticed and many people have been on plaquinel for years with nothing notable while others can't tolerate it. YMMV.