Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil and daypro used together Hydroxychloroquine monitoring ophthalmology Plaquenil and tinazidole Plaquenil info Bone Marrow Suppression is a reduction in the activity of the bone marrow, which is the thick liquid inside some of the bones that produces blood cells. The result is a reduction in red blood cells which carry oxygen, white blood cells which fight infection, and/or platelets which control bleeding. I ran into a friend that has RA and lots of other problems today at a local store and we didn't have much time to talk but we did speak of Plaquenil. she said to be careful with the plaquenil because she has had problems with it. it has affected her bone marrow. something about her bone. Oct 27, 2017 Myelodysplastic syndromes result from something amiss in the spongy material inside your bones where blood cells are made bone marrow. Treatment for myelodysplastic syndromes usually focuses on reducing or preventing complications of the disease and its treatments. In some cases, treatment might involve chemotherapy or a bone marrow transplant. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil bone marrow depression Common and Rare Side Effects for Hydroxychloroquine Oral, Plaquenil and bone marrow. DailyStrength Plaquenil retinal screening guidelinesPlaquenil side effects dry mouthHydroxychloroquine sickle cell Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells but potentially serious eye toxicity can occur. Hydroxychloroquine Plaquenil Side Effects & Dosage for.. Myelodysplastic syndromes - Symptoms and causes - Mayo Clinic. Types of Drugs That Affect Bone Mineral Density. Although the risk of bone marrow depression is low, periodic blood counts are advisable as anaemia, aplastic anaemia, agranulocytosis, a decrease in white blood cells, and thrombocytopenia have been reported. Plaquenil should be discontinued if abnormalities develop. Bone marrow suppression refers to a decrease in the ability of the bone marrow to manufacture cells, and is common with chemotherapy. In addition to eliminating cancer cells, chemotherapy drugs eliminate normal cells that divide rapidly, such as those in the bone marrow that form the different types of blood cells. Plaquenil Side Effects. Generic Name. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. Bone-marrow depression, anemia.