Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Can plaquenil cause diarrhea Macular oct changes in plaquenil toxicity Chloroquine transfection lipofectamine Chloroquine phosphate toxic May 07, 2019 Plaquenil hydroxychloroquine is commonly used to help keep mild lupus-related problems, such as skin and joint disease, under control. This drug is also effective at preventing lupus flares. The Lupus Foundation of America. American College of Rheumatology. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Substitutes for plaquenil Hydroxychloroquine Side Effects, Dosage, Uses, and More, Hydroxychloroquine Plaquenil Can i have occasional glass wine plaquenilHydroxychloroquine programChloroquine defineChloroquine sensitive areas I to have been taking plaquenil for at least 6 to 8 months not sure a lil lupie lol anyway and i do feel a difference in my eyes plus my liver enzymes are up i believe that the highest is 47 and mines is 48 the doc says not dangerously high but we need to keep an eye on it. im not sure but i thought that the enzymes were up cuz of the prednisone but now ill have to ask the doc. i too want. Alternative" to plaquenil. ProHealth Fibromyalgia, ME/CFS and Lyme.. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Common and Rare Side Effects for Plaquenil Oral. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. My rheumy has just prescribed Plaquenil for my SS. Reading the warnings, I see that there is concern about effects on the eyes retinas. I am very concerned about this and am wondering if anyone out there has been put on an alternative drug to treat their SS. I have several issues with my. I "know" I need some meds, but cannot tolerate Plaquenil. Wondering if anyone has come across something "natural" that mimics it. Thanks & LIGHT*****carole - Hi, Carole. When I started Plaquenil, my GI system was in an uproar. But it usually was anyway. I didn't realize, until I saw Dr.