Please review the following URL and make sure that it is spelled correctly. Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Aralen 150 mg Chloroquine scheduled drug Does hydroxychloroquine affect the kidneys Cheap aralen 500mg Rheumatoid Arthritis. The action of hydroxychloroquine is cumulative and may require weeks to months to achieve the maximum therapeutic effect see CLINICAL PHARMACOLOGY. Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. In a small percentage of patients, side. The recommended Plaquenil dosage for malaria prevention is 400 mg once weekly, starting two weeks before the anticipated exposure. The usual starting dosage for treating lupus is 400 mg once or twice a day, and the recommended starting dose for the treatment of rheumatoid arthritis is 400 to 600 mg daily. Renal clearance in rheumatoid arthritis patients taking PLAQUENIL for at least six months seemed to be similar to that of the single dose studies in volunteers, suggesting that no change occurs with chronic dosing. Range for renal clearance of unchanged drug was approximately 16 to 30% and did not correlate with creatinine clearance; therefore. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Plaquenil dosing for ra Hydroxychloroquine dosage recommendations often ignored MDedge., Plaquenil Dosage - Antibiotics Home Page Plasmodium falciparum chloroquine resistancePlaquenil drug interactions side effectsHalf life of chloroquine Renal clearance in rheumatoid arthritis RA patients taking PLAQUENIL for at least six months seemed to be similar to that of the single dose studies in volunteers, suggesting that no change occurs with chronic dosing. PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Hydroxychloroquine Plaquenil. The Hydroxychloroquine Dosing Calculator calculates appropriate daily dose of hydroxychloroquine. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. What Conditions Does This Treat? Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective. Now it is generally used for rheumatoid arthritis, but it has also been shown to work well for juvenile arthritis, some lupus symptoms, and other types of autoimmune conditions.