One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Plaquenil dosages Hydroxychloroquine sulfate for ra Plaquenil cause itching Chloroquine resistant malaria meaning PLAQUENIL should be administered with caution in patients having glucose-6-phosphate dehydrogenase G-6-PD deficiency. Dermatologic Effects. Dermatologic reactions to PLAQUENIL may occur and, therefore, proper care should be exercised when it is administered to any patient receiving a drug with a significant tendency to produce dermatitis. The drusen-like deposits were located in a ring-shaped distribution between the retinal pigment epithelium and Bruch's membrane, with the majority of eyes having macular sparing. In patients with glomerulonephritis, the drusen-like deposits were more numerous than in those systemic lupus erythematosus patients without renal involvement. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil drusen deposits Recommendations on Screening for Chloroquine and., Drusen-Like Deposits Common in Young Adults With Systemic. Prednisone and hydroxychloroquine interactionPlaquenil drug classesChloroquine phosphate toxicCan hydroxychloroquine stop bone graft osseointegration Click to email this to a friend Opens in new window Click to share on Twitter Opens in new window Click to share on Pocket Opens in new window Plaquenil Toxicity - OCTMD. Plaquenil Side Effects Common, Severe, Long Term -. Plaquenil Uses, Dosage & Side Effects -. Multimodal imaging set showing drusen-like deposits DLDs affecting both eyes in a patient diagnosed with systemic lupus erythematosus SLE. In the color fundus photographs Top/Third rows, left, DLDs are seen as multiple yellowish lesions of different sizes spread across the posterior pole, but mainly located in the temporal region. Well I had my regular ophthalmology appointment today and the doc said he sees drusen in my eye. He said that its a pre-sign to macular degeneration which can lead to partial blindness. Because of my age I'll be 32 this month it is very rare. Thing is he didn't see it back in January when I went for my baseline appt before starting Plaq. I have had a large number of drusen in my retina for about 10 year. The other day when I was at the opthamologist, for my visual field test for plaquenil, the assistant said I needed to be dilated because "having macular degeneration means thatyou need to be dialted every 6 months" I replied, no.