Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. 60 increase in malaria deaths after chloroquine failure Hydroxychloroquine and ed How to wean from plaquenil Dosing recommendations in lupus erythematosus. For the treatment of cutaneous lupus erythematosus, the usual dose range is 200–400 mg daily until a therapeutic response is achieved. Although maximum doses were previously calculated on the patient's ideal body weight and advised not to exceed 6.5 mg/kg/days, dosing is now recommended not to. Cutaneous lupus erythematosus CLE is an autoimmune, inflammatory skin disease seen in patients with or without systemic lupus erythematosus SLE. The management of CLE includes treatment and prevention of lesions, as well as routine assessment for systemic disease. Treatment options include both topical and systemic therapies. Ocular toxicity is unlikely if the dose of chloroquine phosphate does not exceed 4 mg/kg daily equivalent to chloroquine base approx. 2.5 mg/kg daily. For rheumatoid arthritis and lupus erythematosus, reduce dose. Monitoring requirements. Monitoring of patient parameters. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Chloroquine lupus dose Aralen Chloroquine MyLupusTeam - Lupus Support Online, Treatment of Cutaneous Lupus - PubMed Central PMC Perg for plaquenil If you are also taking kaolin or antacids, take them at least 4 hours before or after using chloroquine. If you are also taking ampicillin, take it at least 2 hours before or after using this medicine. Dosing. The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. Chloroquine Oral Route Proper Use - Mayo Clinic. CHLOROQUINE Drug BNF content published by NICE. Hydroxychloroquine Uses, Dosage & Side Effects -. For treatment of acute attacks of malaria in adults, one dose is usually taken right away, followed by half the dose 6 to 8 hours later and then half the dose once a day for the next 2 days. For prevention and treatment of malaria in infants and children, the amount of chloroquine phosphate is based on the child's weight. Usual Adult Dose for Malaria Prophylaxis. 500 mg chloroquine phosphate 300 mg base orally on the same day each week Comments-If possible, suppressive therapy should start 2 weeks prior to exposure; if unable to start 2 weeks before exposure, an initial loading dose of 1 g chloroquine phosphate 600 mg base may be taken orally in 2 divided doses, 6 hours apart. Hydroxychloroquine is generally prescribed at a daily dose of 6.5 milligrams or less per kilogram of body weight. Using this formula, the dosage for a 150-pound person would be 443 mg/day, as one kilogram equals 2.2 pounds. Because HCQ is formulated as a 200 mg tablet, many people taking it for lupus will take two pills per day.