This medicine is also sometimes given off-label to help the following conditions: Also, let your doctor know if you drink large amounts of alcohol before starting on this medicine. Your doctor will probably want to order frequent tests to check your body's response to chloroquine. Plaquenil reduces preeclampsia Antimalarial drugs hydroxychloroquine Non-chloroquine-resistant. 1 g 600 mg base PO, THEN; 500 mg 300 mg base PO 6-8 hours later, THEN; 500 mg 300 mg base PO at 24 hours & 48 hours after initial dose; Amebiasis, Extraintestinal. 1 g 600 mg base PO qDay for 2 days, THEN. 500 mg 300 mg base qDay for 14-21 days. Porphyria Cutanea Tarda Off-label 125-250 mg 75-150 mg base PO twice weekly The dosage of chloroquine phosphate is often expressed in terms of equivalent chloroquine base. Each 250 mg tablet of chloroquine phosphate is equivalent to 150 mg base and each 500 mg tablet of chloroquine phosphate is equivalent to 300 mg base. Malaria Information and Prophylaxis by Country; Country Areas with Malaria Drug Resistance 2 Malaria Species 3 Recommended Chemoprophylaxis 4 Key Information Needed and Helpful Links to Assess Need for Prophylaxis for Select Countries; Democratic Republic of the Congo Congo-Kinshasa All Chloroquine P. falciparum 90%, P. ovale 5%, P. vivax rare Let your healthcare provider know if your symptoms either don't improve or worsen while taking this medicine. Keep all appointments with your doctor and laboratory. Chloroquine prophylaxis dosage Aralen Chloroquine Uses, Dosage, Side Effects., CHLOROQUINE PHOSPHATE TABLETS, USP 250 MG and 500 MG Plaquenil coffee Prophylaxis against Chloroquine-sensitive Plasmodium species Prophylaxis against Chloroquine-sensitive Plasmodium species Adult Dose The dosage for prophylaxis is 500 mg = 300 mg base administered once per week on exactly the same day of each week. Chloroquine - FDA prescribing information, side effects.. Malaria Information and Prophylaxis, by Country D - CDC. Chloroquine Dosage Guide with Precautions -. Both adults and children should take one dose of chloroquine per week starting at least 1 week before. traveling to the area where malaria transmission occurs. They should take one dose per week while there, and for 4 consecutive weeks after leaving. The weekly dosage for adults is 300mg base 500mg salt. Where facilities for intravenous infusion are not available chloroquine can be administered by intramuscular or subcutaneous injection at a dosage of 2.5 mg/kg every 4 hours or 3.5 mg/kg every 6 hours until a total of 25 mg/kg has been given. Malaria treatment oral To treat malaria in adults, one dose of oral chloroquine is usually given right away. Then, half the dose is taken six to eight hours later. This is typically followed by half the dose once a day for the next two days. Amebiasis treatment oral To treat amebiasis in adults.