It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Hydroxychloroquine 200 mg without prescription Plasmodium resistance to chloroquine Hydroxychloroquine HCQ is a commonly used drug that has been linked to drug-induced cardiomyopathy. A 57 year old female with a history of systemic lupus erythematosus stable on HCQ for 30 years and known MYBPC3 gene positive hypertrophic cardiomyopathy HCM presented with decompensated heart On the basis of these classic findings, a diagnosis of hydroxychloroquine cardiomyopathy was made, and the drug was discontinued. Three months later her symptoms had completely resolved. Repeat imaging using cardiac magnetic resonance demonstrated an ejection fraction of 65% D, Online Video 2. We present a case of twin sisters who both suffered from systemic lupus erythematosus SLE and HCQ-induced cardiomyopathy presenting with decompensated heart failure HF, suggesting that genetic predisposition might be a factor in HCQ-induced cardiomyopathy. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Hydroxychloroquine induced cardiomyopathy and heart failure in twins PDF Hydroxychloroquine-induced cardiomyopathy a case., Hydroxychloroquine A Treatable Cause of Cardiomyopathy. Plaquenil brandIs plaquenil toxicity reversibleCan i take ginseng with plaquenil New clinical and ultrastructural findings in hydroxychloroquine-induced cardiomyopathy. A 47-year-old man with systemic lupus erythematosus and heart failure. Hydroxychloroquine cardiotoxicity presenting as a rapidly.. Hydroxychloroquine-induced cardiomyopathy and heart failure.. Hydroxychloroquine-Induced Cardiomyopathy Circulation.. Genetic predisposition for HCQ‐induced cardiomyopathy was first proposed in a set of twin sisters who both suffered from SLE. 9 Chatre et al. described a case of a 61‐year‐old woman whose diagnosis of α‐galactosidase A deficiency was unmasked by chronic HCQ treatment. 10 Because Fabry disease and other lysosomal storage disorders, such. Drug-induced cardiotoxicity including chemotherapy-induced cardiotoxicity remains an important cause of heart disease and heart failure.1, 2, 3 Cardiomyopathy from cancer chemotherapy is well recognized as a drug-induced complication but the cardiotoxicity from other drugs is not well described.2, 3 Chloroquine CQ and hydroxychloroquine HCQ are 4-aminoquinolines 4 at one time commonly used. Abstract. Chloroquine Hydroxychloroquine-induced cardiomyopathy is a rare but potentially life-threatening condition. Cessation of the culprit drug, along with aggressive afterload reduction therapy, has been associated with halting of disease progress and even improvement in patients' clinical and histologic status.