My husband has been taking Plaquenil (generic hydroxychloroquine) for almost 2 yrs., under a rheumatologist's care. He became very ill, and was diagnosed w/ viral meningial encephalitis. We were much later told that the Plaquenil had "lowered his tolerance to infection, as it is also an immuno-suppressant." In essence, the medicine allowed the viral infection to cross the barrier between his brain and blood/lungs. How long does it take plaquenil to reach steady state Hydroxychloroquine and ibuprofen Plaquenil safer than floroquinolones Plaquenil testing icd 10 Mefloquine and other drugs known to lower the convulsive threshold Plaquenil can lower the convulsive threshold. Co-administration of Plaquenil with other antimalarials known to lower the convulsion threshold e.g. mefloquine may increase the risk of convulsions. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Aug 14, 2017 Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. (He was never told of that risk when he was put on the medication.) Added : What I failed to mention (above) is that he almost died in April when this happened. His/our question is as to whether he can or should EVER go back on the medication and risk exposure to further illnesses if it is true that Plaquenil or the generic for is, in fact, an immuno-suppressant and presents a serious health risk for him? Can plaquenil lower your calcium numbers How to Reduce Hypercalcemia High Calcium Levels Naturally, Plaquenil Uses, Dosage & Side Effects - Synthesis of chloroquine phosphate pptPlaquenil medication side effects Plaquenil reduces inflammation in many Rheumatic disorders, the mode of action is pretty complicated though so I shan't bore you with all the details, but basically it prevents your dendritic cells these are messengers for your immune system, if you will from interacting with your T-Cells a special type of white blood cell which through a convoluted and boring process, causes inflammation. Inflammatory Osteoarthritis And Plaquenil. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Hydroxychloroquine Plaquenil. Low Blood Counts Due To Bone Marrow Failure; Low Blood Sugar; Low Levels Of A Type Of White Blood Cell Called Neutrophils; Low Levels Of White Blood Cells; Maculopathy; Mental Problems From Taking. Aug 02, 2010 Basically, the immune system is a bit out of control. Plaquenil works by suppressing the immune system. Unfortunately you can't tell it to attack just the germs so you suppress all of its function to spare your healthy tissue- in your husband's case, his eyes, mouth, throat. NOTE Plaquinil and hydroxychloroquine are essentially the same drug. Increased secretion of the hormone can increase calcium levels in the blood. Effects of Hypercalcemia. Normal blood calcium levels, according to Medline Plus, are between 8.5 and 10.2 milligrams per deciliter, with levels above that considered hypercalcemia 2. Hypercalcemia can lead to health problems such as renal insufficiency, vascular and soft tissue calcification, and kidney stones.