Please review the following URL and make sure that it is spelled correctly. Plaquenil (Hydroxychloroquine sulfate) is a drug originally used to prevent or treat malaria. Plaquenil and methylprednisolone Hydroxychloroquine for psoriasis Plaquenil canadian drug plan Chloroquine solubility dmso Our Plaquenil hydroxychloroquine Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Focus on Eyes Long-term Plaquenil intake can affect your vision. Taking high doses or long-term treatment of Plaquenil, an anti-malaria drug used to treat lupus, can lead to vision problems. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria 2. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA 1. Now the drug is used to treat inflammatory diseases. Malaria is a serious but rare disease caused by bites from infected mosquitos. Hydroxychloroquine effect on eyes Hydroxychloroquine DermNet NZ, Focus on Eyes Long-term Plaquenil intake can affect your vision Chloroquine diphosphate selleckchemPlaquenil and inflammation levelsMental side effects of plaquenilLdn instead of plaquenil One of the most serious side effects is a toxicity in the eye generally with chronic use. People taking 400 mg of hydroxychloroquine or less per day generally have a negligible risk of macular toxicity, whereas the risk begins to go up when a person takes the medication over 5 years or has a cumulative dose of more than 1000 grams. Hydroxychloroquine - Wikipedia. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Plaquenil. There is a small risk that hydroxychloroquine can damage your retina part of the eye, and this increases with long-term use and higher dosage. Your doctor will advise you on a safe dose to take according to your weight, and you will need to have regular monitoring of your eyes. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage associated with long-term use of the antimalarial drugs hydroxychloroquine brand name Plaquenil® and chloroquine. Improved vision screening tests and updated dosing guidelines are key to avoiding such complications.