I started on it just less than 2 weeks ago, and I'm surrounded by ill people at work and already have a bit of a cold (nothing severe). it is "milder" than a lot of the other dmards in terms of side effects and activity x It is listed as having a mild immunosuppressant effect in my book on RA, but one of the reasons for the blood tests is to check that your immune system is not being suppressed too much (eg checking your white blood cell levels), so you shouldn't be completely vulnerable. Even after several years of taking lots of drugs I've not found any difference in the number of colds etc I get, and loads of people on here are teachers etc who get a lot of exposure to colds and coughs without too much problem. Long term use of plaquenil Hydroxychloroquine toxicity retina I am immunocompromised. My immune system doesn't work to protect me. The FACTORS that make up our immune system A, G, M, E are abnormally low in my blood. So my body doesn't fight off infections, viral, bacterial or fungal. So I have a Primary Immune Deficiency Disorder. Before I knew this about myself, I had the Shingles Vaccine in 2007. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. It's important to watch for possible side effects and toxicity. For people who weigh less than 80 kg, a lower daily dose is prescribed, up to a maximum of 5 mg/kg of body weight. Mar 03, 2020 Though individual risk for and response to infectious diseases varies, people living with autoimmune conditions, such as inflammatory forms of arthritis, may be at greater risk of infection or complications. In addition, some of the medicines that treat autoimmune conditions further suppress the immune system. Polly Thank you both, I thought it shouldn't be too bad and that it's pretty mild in comparison to other drugs. Always better to be well informed and I remember the consultant saying its bit a bad time of year to start on it as I've missed all the bugs round Christmas time so thought there may be a slim chance of it being suppressed. But do look after yourself, and make sure you eat well and don't get too tired as if you have a cold already you need to pamper yourself a bit more than you would have before RA. Does plaquenil suppress immune system further in an immunosuppressed person Immune System Suppression Patient, Taking Plaquenil for Rheumatoid Arthritis Plaquenil tablets دواء For people with inflammatory arthritis, your immune system tends to focus on attacking your own body rather than outside threats like the coronavirus. And some of the medications used to manage these diseases also suppress the immune system, which can make patients more vulnerable to infection. Coronvirus Facts for Chronic Illness Patients Who Are.. Expert advice about coronavirus in immunocompromised.. Anyone on Hydroxychloroquine plaquenil - Autoimmune.. Plaquenil and its affect on the immune system. Any one have any experience or info regarding pre-existing precancerous conditions and the effects of Plaquenil on the immune system. I see so much info on the net where some says that Plaquenil has very mild effect on immune system except for eye issues --- Other info says it is an. Dear Dr. Aviva, Given I am 56 and have Hashimoto's - an autoimmune condition - am I at higher risk - for getting COVID-19? Should those of us with autoimmune conditions consider that to be an “underlying condition” that puts one at higher risk of having a more severe reaction if infected with the coronavirus. Thank you so much for Jul 25, 2010 But she also stopped the use of enbrel Enbrel helps to keep the immune system from attacking the body, which improves symptoms and, in some cases, prevents future damage from occurring. RA is a chronic, systemic inflammatory disorder that may affect many tissues and organs, but principally attacks synovial joints.