Please review the following URL and make sure that it is spelled correctly. This article focuses upon hydroxychloroquine retinopathy. Chloroquine was originally used as an anti-malarial therapeutic. Hydroxychloroquine and ibuprofen Withdrawal from plaquenil Hydroxychloroquine rheumatoid arthritis History hydroxychloroquine lupus Because the retinal damage from plaquenil is usually irreversible if present for a more prolonged period of time, it is important to detect the disease in its early stages. All of the diagnostic test results confirmed the initial diagnosis of early retinal toxicity from plaquenil therapy. The newest electronic color vision diagnostics that are highly sensitive and specific provide physicians with a new diagnostic tool that may also be helpful for easily assessing changes over time that was not possible with historically used printed color test books. Konan’s ColorDx CCT HD is an example of a comprehensive color vision. Cessation of plaquenil is the standard-of-care treatment for plaquenil-induced toxic maculopathy. If the patient has Possible Early Toxicity Cessation of plaquenil if possible or follow-up at 3 to 6 month intervals until there is further evidence to rule out toxicity; If the patient has Probable Toxicity In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. Color dx konan in plaquenil toxicity ColorDx CCT HD color vision diagnostics Konan Medical, ColorDx Specs FAQ Register Konan Medical Primaquine and chloroquine are drugs used in the treatment infectionsDrug instead of hydroxychloroquine To reduce the incidence of chloroquine and hydroxychloroquine toxicity, health care providers HCP's that prescribe these medications and those that screen for ocular toxicity have developed clear dosing and screening protocols that have reduced the risk of end-stage disease; bull's eye maculopathy and central vision loss Level I. Chloroquine And Hydroxychloroquine Toxicity - StatPearls.. H35.381-383 Toxic Maculopathy Of Retina - Decision-Maker PLUS. Multimodal Imaging in Plaquenil Toxicity. ColorDx by Konan is another option for testing color vision. for example, due to Plaquenil toxicity or degenerative pathology, the patient may experience a tritan deficiency. The test has. Red, orange, yellow, and yellow-green appear somewhat shifted in “hue” another word for color towards green and appear less intense that they do to a color normal observer. The redness portion of a violet or lavender color is also weakened with a Protan so what appears contains mostly the blue component of the color. Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1.