White blood cells (also called leukocytes) are part of the immune system, and they are the cells that protect your body against infections by bacteria, viruses, fungi, and parasites. The microorganisms that cause diseases are literally everywhere, but most people do not get sick because they have ample numbers of white blood cells providing protection. Low white blood cell count is also known as leukopenia. Low white blood cell count often means there is a problem in the body, so it is not considered normal. Each has their own specialized purposes and different life spans. Macrobid and hydroxy chloroquine interactions Plaquenil sudden neck stiff neck pain From research I have done online, I gather that low white cell count can also be a symptom of the Sjogrens in itself. I have also received a copy of a letter from my rheumatologist to my doctor thanking her for the notification of my low neutrophils count of 1.2 and acknowledging her stopping the Plaquenil but not offering any alternative. Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells anemia. Aug 14, 2017 Blood Disorders. According to the New Zealand Dermatological Society, Plaquenil can cause abnormalities in blood counts. An abnormally low number of white blood cells can lead to infection, because white blood cells defend the body against bacteria. Low platelet count thrombocytopenia can lead to easy bleeding and bruising. Our body produces millions of different white blood cells continuously that replace worn out or dead ones. There are monocytes (morphs into other white blood cells), lymphocytes (releases antibodies, regulates immunity, and kills infected human cells), basophils (initiates inflammatory reactions), eosinophils (kills parasites and triggers allergic reactions), and neutrophils (main killers of bacteria and fungi). Can hydroxychloroquine cause low white blood cell count Long-Term Side Effects of Plaquenil for Rheumatoid., Hydroxychloroquine Plaquenil Side Effects & Dosage for. PlaquenilCan plaquenil lower blood pressureBenefits of using plaquenilSplitting hydroxychloroquinePlaquenil maculopathy photos Continued Follow-up Tests. If there's no clear reason for a low white blood cell count, your doctor will probably want to do the test again, or do a differential or "diff" along with the CBC. Low White Blood Cell Count 6 Possible Causes for a Low WBC. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Low white blood cell count - Mayo Clinic. White blood cells are manufactured in bone marrow — the spongy tissue inside some of your larger bones. A low white blood cell count usually is caused by Viral infections that temporarily disrupt the work of bone marrow. Certain disorders present at birth congenital that involve diminished bone marrow function. Druginformer Identified Side Effects White blood cell count. Posted By Anonymous in on August 17, 2010 @ am “ Side Effects low white blood cell count I absolutely loved Plaquenil. I had saliva and the swelling in my joints was gone. In some cases, a vitamin or mineral deficiency can cause the white blood cell count to drop significantly. This is commonly associated with a copper and zinc deficiency, though a low red and white blood cell count may also be due to a lack of iron or vitamin B12 in the diet.