Although survival rates have improved, over one half of patients with systemic lupus erythematosus have permanent damage in one or more organ systems. Arthritis and cutaneous manifestations are most common, but renal, hematologic and neurologic manifestations contribute largely to morbidity and mortality. Chloroquine phosphate uk Hydroxychloroquine monitoring parameters Hydroxychloroquine tablets in hindi Hair loss hydroxychloroquine Results This article reports successful treatment of refractory hypertrophic discoid lupus with combination therapy that included chloroquine 250 mg/d, quinacrine 100 mg/d, and actitretin 25 mg/d. In active rheumatoid arthritis and systemic and discoid lupus erythematosus, to avoid excessive dosage in obese patients, the daily maximum dose should be calculated on the basis of ideal body weight. Chloroquine is a synthetic antimalarial medication that was first developed in 1934. In addition to its antimalarial effects, chloroquine has been used extensively in rheumatology and dermatology since the 1950s. Discoid lupus erythematosus. Reticular erythematous mucinosis. Systemic lupus erythematosus has fascinated physicians for almost a century and remains the prototypic autoimmune disease. Treatment approaches emphasize using a combination of drugs to minimize chronic exposure to corticosteroids. Chloroquine for discoid lupus CHLOROQUINE DIPHOSPHATE IN TREATMENT OF DISCOID LUPUS., CHLOROQUINE Drug BNF content published by NICE Does plaquenil show up on a drug testChloroquine antibodyScreening criteria for ocular toxicity of plaquenil Cutaneous lupus erythematosus CLE is an autoimmune, inflammatory skin disease seen in patients with or without systemic lupus erythematosus SLE. The management of CLE includes treatment and prevention of lesions, as well as routine assessment for systemic disease. Treatment options include both topical and systemic therapies. Treatment of Cutaneous Lupus. Chloroquine DermNet NZ. Treatment of Cutaneous Lupus Erythematosus. Are You Confident of the Diagnosis? Discoid lupus erythematosus DLE is a form of chronic cutaneous lupus erythematosus CCLE. A diagnosis of discoid lupus erythematosus can be made with the characteristic clinical appearance and location of cutaneous lesions together with histopathologic confirmation. It is a photosensitive dermatosis, but there may not be a clear temporal Chloroquine phosphate is used occasionally to decrease the symptoms of rheumatoid arthritis and to treat systemic and discoid lupus erythematosus, scleroderma, pemphigus, lichen planus, polymyositis, sarcoidosis, and porphyria cutanea tarda. Talk to your doctor about the possible risks of using this drug for your condition. A trial conducted in 1953 investigated the effects of Chloroquine Aralen treatment on 30 people with discoid lupus. Researchers concluded that treatment with Chloroquine furnished significant improvement in early cases of dermatological lupus symptoms. Side effects Most people do not experience side effects from taking Aralen.