These drugs are called disease-modifying antirheumatic drugs (DMARDs), and they are an important part of an overall treatment plan. Disease-modifying drugs act on the immune system to slow the progression of rheumatoid arthritis. This is why they are called "disease-modifying." Many different drugs can be used as DMARDs in the treatment of RA, but some are used more often than others. The drug plaquenil Plaquenil skin reaction Chloroquine dose for malaria prophylaxis Can plaquenil cause headaches Prednisone is a bone killer as I’m paying the price 25 years later, but I was pretty pain free all those years! No hair loss and plaquenil has not affected my eyes other than dry eyes. Keep a diary of your meds. What Conditions Does This Treat? Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective. Now it is generally used for rheumatoid arthritis, but it has also been shown to work well for juvenile arthritis, some lupus symptoms, and other types of autoimmune conditions. Plaquenil hydroxychloroquine and prednisone are used to treat symptoms of rheumatoid arthritis. Plaquenil is also used to treat or prevent malaria, and to treat symptoms of discoid or systemic lupus erythematosus. Prednisone is also used to treat or manage many conditions. They are not as powerful as other DMARDs, but they usually cause fewer side effects. Hydroxychloroquine (Plaquenil) and sulfasalazine (Azulfidine) are used for mild rheumatoid arthritis. Plaquenil and prednisone for rheumatoid arthritis Inflammatory Osteoarthritis And Plaquenil, RA and Hydroxychloroquine How Effective is it for Rheumatoid. Hydroxychloroquine cardiac side effectsSplitting hydroxychloroquinePlaquenil mouth sores Aug 22, 2008 Plaq is not a substitute for prednisone. Prednisone is an intermediate acting corticosteroid-which means it has direct anti-inflamitory properties that take effect begining in a few hours. It is ment to get this undercontrol now and diminish your pain. Plaq is a longer time medication it may take two months before their is a noticable difference. Prednisone/Plaquenil question -. Plaquenil vs. Prednisone Prescription Treatment for.. Prednisone, Sulfasalazine, Plaquenil, & now Simponi.. Mar 08, 2010 Medicines which fight the Rheumatoid Arthritis disease activity are called disease modifying anti-rheumatic drugs DMARDs. Rheumatoid arthritis usually requires both disease treatment and symptom treatment. Lately, I’ve given a lot of thought to the prednisone Rheumatoid Arthritis issue. Like so many other RA issues, the prednisone one is huge. User Reviews for Plaquenil to treat Rheumatoid Arthritis. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Many people with rheumatoid arthritis RA can silence their symptoms and halt progression of the disease thanks to biologics, targeted DMARDs and more aggressive treatment approaches. Yet some patients who achieve remission struggle to sustain it. Defining Remission. Remission means different things to different people.