Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil for angioedema Chloroquine suicide Hydroxychloroquine side effects nhs What happens is you mix hydroxychloroquine with alcohol My weight gain is from the steroids I'm certain and not the Plaquenil. Are you on anything else to treat your lupus other than the Plaquenil? If you're on steroids that can be whats causing you to gain weight. I can't offer any advice on losing the weight if you come off the Plaquenil. Weight gain while on Plaquenil? I'm curious if anyone else has experienced weight gain after beginning treatment with plaquenil. I know that the medication is known to cause weight loss and decreased appetite, but I've found that since starting treatment I've gained weight and nothing seems to budge it. Water Retention/ Weight Gain; In summary Plaquenil isn't causing tyour new problems. It probably caused only the nausea, diarrhea, stomach cramps, and intense vertigo. BTW 100 mg daily may reduce side effects, but this low dosage also greatly annihilates its positive effects. 100 mg are a drop maybe two. on a hot stone. And finally Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Weiggt gain tryibg to get off plaquenil Insulin and weight gain Keep the pounds off - Mayo Clinic, Weight gain while on Plaquenil? lupus Chloroquine md anderson I have been on 400mg of Plaquenil since July of 2009 and it was increased to 600mg in October of 2010. I have not had any weight gain or increase in appetite. I have gained weight when I was not feeling well and was less active or when I was on high doses of prednisone. Best wishes Plaquenil and weight gain?. Plaquenil side effects - kidney problems? - Symptoms.. Going off Plaquenil - Sclero Forums MAIN - Sclero Forums. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up. Has anyone's doctor suggested taking plaquenil to help taper off Rheum thinks that plaquenil will help me get to a lower dose of prednisone since I can't get past 7.5 mg without a flare. But what about when you go off of it? In case you’ve been thinking about it. Search. a third gain weight. these are all cues that some women look for if they're trying to get pregnant.