Ophthalmologists play a vital role in educating both patients and prescribing physicians about the risk of toxicity associated with exposure to hydroxychloroquine (HCQ) and chloroquine (CQ) drugs. Because the damage from these drugs is irreversible, knowledge of proper dosages and familiarity with the signs of early stage retinopathy are critical for preventing central vision loss. Antimalarial resistance chloroquine Chloroquine phosphate 250 mg Plaquenil brand manufacturer Three reports from the American Academy of Ophthalmology AAO in 2002, 2011, and 2016 have provided clinicians with evidence-based guidelines for screening patients on CQ/HCQ therapy. Baseline testing within the first year of starting therapy should include a dilated fundus exam to document pre-existing retinal pathology. This information is brought to you by Rheumatology Network and is not sponsored by, nor a part of, the American College of Rheumatology. Hydroxychloroquine HCQ dosing took center stage on October 21 as the focus of the “Great Debate” at the 2018 American College of Rheumatology ACR/Association of Rheumatology Health Professionals ARHP Annual Meeting in Chicago, Illinois. The American Academy of Ophthalmology released an updated set of screening recommendations for hydroxychloroquine Plaquenil and chloroquine to account for the many studies that have shown the effects of these medications on the retina 1. It succinctly makes the case for screening, and The patient can be advised about the risk of further visual loss depending on the severity of the retinopathy. Summary of dosing guidelines Once definitive signs of retinopathy are recognized, the decision to stop medication should be made in conjunction with the patient and the prescribing physician to ensure that medical risks, such as a potential flare of systemic lupus erythematosus (SLE), are managed. Aao plaquenil guidelines 2018 AAO Screening Guidelines for Plaquenil, The Great Debate at ACR 2018 Hydroxychloroquine Dosing. Chloroquine phosphate dosage in childHydroxychloroquine eye issues AMERICAN COLLEGE OF RHEUMATOLOGY POSITION STATEMENT SUBJECT Screening for Hydroxychloroquine Retinopathy. 1 Hydroxychloroquine HCQ, brand name Plaquenil is commonly used for the long-term. Toward this end, the American Academy of Ophthalmology AAO has 18 published guidelines for retinal toxicity monitoring 4, 5. AMERICAN COLLEGE OF RHEUMATOLOGY. Hydroxychloroquine And Chloroquine Screening 2016 AAO.. RCOphth guideline Hydroxychloroquine and Chloroquine.. Guideline Summaries Ophthalmology. Free access to quick-reference Ophthalmology guidelines. Find clinical practice guideline summaries for the Ophthalmology medical specialty area. These clinical guideline tools are designed to assist clinicians in evidence-based best practices and improving patient outcomes. Illustration by April Brust. At the 2018 ACR/ARHP Annual Meeting, I had the opportunity to co-moderate this year's Great Debate, which was titled "Guidelines for SLE HCQ Dose Should Be No More Than 5 mg/kg In All Patients." Based on new data, the authors have revised the Academy’s 2011 guidelines to make screening recommendations more concise and practical. Ophthalmologists play a vital role in educating both patients and prescribing physicians about the risk of toxicity associated with exposure to hydroxychloroquine HCQ and chloroquine CQ drugs.