When I do sleep, upon waking it feels like I never slept. Is this a common side effect and will it subside with time? Can i take a multivitamin with hydroxychloroquine Effect of plaquenil on free light chains Hydroxychloroquine hair lightening Sometimes realizing what’s upsetting you so you can deal with it can improve sleep. Medications and Sleep Some common RA medications may also contribute to sleeplessness. One is the steroid prednisone, which can cause insomnia, agitation or depression. Taking it earlier in the day is best, says Dr. Rosian. Another is hydroxychloroquine Plaquenil. It can sometimes causes people to get jumpy, nervous and twitchy. Taking both drugs at the same time can increase the risk of damage. Can You Take Ibuprofen and Plaquenil Together? Plaquenil has been used safely in combination with salicylates aspirin, non-steroidal anti-inflammatory drugs such as ibuprofen, methotrexate and corticosteroids. What Should You Tell Your Doctor Before Taking Plaquenil? Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Hello I have just been reading that plaquenil can cause insomnia and nightmares which I suffer with. Ive helped x Never taken mine at night so can't comment on that. I read the insert that came with the prescription and it didn't mention insomnia. Can i take plaquenil at night New to Plaquenil - question for you, Canada Plaquenil - Canadian Drugs for Rheumatoid Arthritis and Lupus Is plaquenil an nsaidPlaquenil high anion gap ketoacidosis What should I avoid while taking Plaquenil? Avoid taking an antacid or Kaopectate kaolin-pectin within 4 hours before or after you take hydroxychloroquine. Some antacids can make it harder for your body to absorb hydroxychloroquine. Plaquenil side effects Plaquenil Uses, Dosage & Side Effects -. Hydroxychloroquine Side Effects Common, Severe, Long Term.. Plaquenil Side Effects Go Away? DailyStrength. Apr 12, 2011 According to her, the dizzy and lightheadedness weren't normal side effects of Plaquenil, but the nausea and stomach stuff was. So to make sure it wasn't a bug or anything, she wanted me to go back on it. Then, I was taking it at night, with dinner. For the most part, most of the above symptoms went away. I have just been reading that plaquenil can cause insomnia and nightmares which I suffer with. I take my plaquenil with my evening meal. When is the best time to take it? Would it be best in the morning? I also take in the morning thyroxine, omeprazole and co-codamol, would it interfere with any of those if I took it in the morning instead of. How to use Plaquenil. Lupus and/or rheumatoid arthritis patients will most likely take this medication by mouth, usually once or twice daily or as directed. Hydroxychloroquine generally is given to adults in doses of 200 mg or 400 mg per day. In some cases, higher doses can be used.